A miniaturised smart drug delivery module

31st October 2016

SENSIRION

Enaie Azambuja

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At this year’s COMPAMED trade fair, the sensor manufacturer Sensirion and the Fraunhofer Research Institution for Microsystems and Solid State Technologies (EMFT) will be presenting an innovative concept study in the field of medical technology. Fraunhofer EMFT’s silicon micropump has been combined with Sensirion’s LD20 single-use liquid flow sensor as part of a joint project with the aim of developing a smart and cost-efficient miniaturised module for controlled and monitored drug delivery.

This highly integrated single-use drug delivery module measures a mere 35x15x5mm. Both partners will be at COMPAMED 2016 to showcase live demonstrations for interested visitors for the first time.

Sensirion AG is the leading manufacturer of humidity, temperature, gas and liquid flow sensors. The cost-efficient LD20 disposable liquid flow sensor used for this concept study is exceptionally compact and measures flow rates in the micro and millimeter per hour range with outstanding precision and reliability thanks to the patented CMOSens Technology.

The Fraunhofer EMFT is among the world's leading development teams in the field of micropumps. Scientists at the research institution have developed various micro membrane pumps made of silicon, which can be manufactured in high volumes at wafer level for very low costs. Both partners have received the DeviceMed innovation prize for their advancements in microfluidics in the past.

During a meeting at COMPAMED 2015, Sensirion and Fraunhofer EMFT discussed the idea for an integrated single-use module for a controlled and monitored drug delivery. The innovative concept progressed into a development project that the teams have worked on over the last year.

The objective of the project is to demonstrate the possibilities of such a solution for single-use applications to the medical technology industry. At this year’s COMPAMED, visitors will be able to see the results first-hand and for the first time.

The single-use drug delivery module is a highly integrated microfluidic system based on the Sensirion’s LD20 disposable liquid flow sensor, which can measure even tiniest flow rates with extraordinary speed, precision and intelligence and features sensitive failure detection to help counteract e.g. cross flows and extravasation.

The Fraunhofer EMFT micropump has been seamlessly integrated into the extended flow channel of the sensor and reaches despite its tiny size type dependent flow rates with water of up to 1000 µl/min.

The minimum displaced volume is 50 nanoliters. This single-use drug delivery module opens up entirely new possibilities for wearable and digital applications that will simplify patient compliance.

Visit both project partners Sensirion (Hall 8a, Stand H19.6) and Fraunhofer EMFT (Hall 8a, Stand F34.4) from November 14 – 17, 2016 at COMPAMED in Düsseldorf to learn more about the concept study.