Medical
Creating specialised cells more efficiently
Researchers at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered that a metabolic molecule called alpha-ketoglutarate helps pluripotent stem cells mature early in the process of becoming adult organs and tissues. The findings, published online in the journal Cell Metabolism, could be valuable for scientists working toward stem cell–based therapies for a wide range of diseases.
'Repair system' in algae yields tools for biotechnology
A way of fixing inactive proteins has been discovered in an algae, which uses chloroplast extracts and light to release an interrupting sequence from a protein. Research specialist Stephen Campbell and Professor David Stern at the Boyce Thompson Institute report the discovery in the Journal of Biological Chemistry. This repair system may have applications in agriculture and biotechnology because it could potentially be harnessed to enab...
Enabling the visualisation of oxygen in tissue
Learning how to look inside a body without having to cut it open is still an important part of medical research. One of the great challenges in imaging remains the visualisation of oxygen in tissue. A team led by Prof. Vasilis Ntziachristos, Chair for Biological Imaging at the Technical University of Munich (TUM) and Director of the Institute for Biological and Medical Imaging at the Helmholtz Centre in Munich, has developed an approach to t...
Helping the visually impaired to navigate safely
A recently launched project aimed at developing and testing a portable, electronic assistance system that will greatly extend the range of motion for the visually impaired, will receive €1.7m funding from The Federal Ministry of Education and Research.
Scientists use robot to test cells by the billion
Farnborough-based Peak Analysis and Automation (PAA) designed and built an automated primary antibody screening workcell for early stage development of potential new treatments for central nervous system and immunology disorders, for UCB. PAA built around a Mitsubishi Electric robot, so the workcell speeds up the process of antibody discovery by allowing the screening of billions of antibody producing B cells.
Scrutinising the architecture of synaptic transmission
For more than a century, neuroscientists have known that nerve cells talk to one another across the small gaps between them, a process known as synaptic transmission. Information is carried from one cell to the other by neurotransmitters such as glutamate, dopamine, and serotonin, which activate receptors on the receiving neuron to convey excitatory or inhibitory messages. But beyond this basic outline, the details of how this crucial aspect...
Microchip-based platform measures PNS activity
For the first time, Lawrence Livermore National Laboratory (LLNL) researchers have successfully incorporated adult human peripheral nervous system (PNS) cells on a microelectrode platform for long-term testing of chemical and toxic effects on cell health and function. The study, part of a project known as iCHIP (in-vitro Chip-Based Human Investigational Platform), was recently published online in the journal Analyst.
Improving patient care via open IoT ecosystem
Real-Time Innovations (RTI), the IIoT connectivity platform company, have announced its support and involvement in the Industrial Internet Consortium's (IIC) newest testbed in partnership with Infosys, PTC and the Massachusetts General Hospital MD PnP Lab. The Connected Care Testbed is designed to develop an open IoT data management and analytics platform for clinical and remote medical devices.
Imaging technique reveals brain tissue at multiple scales
MIT researchers have developed a technique for imaging brain tissue at multiple scales, allowing them to peer at molecules within cells or take a wider view of the long-range connections between neurons.
Web-based technology improves paediatric ADHD care
As cases of ADHD continue to rise among U.S. children, pediatricians at busy community practices are getting a much-needed assist from a web-based technology to improve the quality of ADHD care and patient outcomes. According to a multi-institutional study published online in Pediatrics, a web-based software program is helping reduce ADHD behavioural symptoms in children receiving care at community paediatric practices by coordinating care a...